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Is it safe to take 50000 IU of vitamin D weekly?

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For vitamin D deficiency: 50,000 IU per week for 6-12 weeks has been used. However, some patients require higher doses for longer periods of time to maintain optimal blood levels of vitamin D. Finally, 1750- 50,000 IU of vitamin D has been taken in daily or weekly doses for 6-12 months.
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